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Insider Filings - ORBIMED ADVISORS LLC
Last Updated 
11-Dec-16
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ORBIMED ADVISORS LLC: Declared Holdings
Company/RelationshipReportedShares  Ownership
Adaptimmune Therapeutics plc -
Director
NasdaqGS:ADAP
(historical quotes, profile, other insiders)
24-May-1629,753,404  Indirect
Aeglea BioTherapeutics, Inc.
Beneficial Owner (10% or more)
NasdaqGM:AGLE
(historical quotes, profile, other insiders)
12-Apr-161,360,224  Indirect
Audentes Therapeutics, Inc.
Director
NasdaqGM:BOLD
(historical quotes, profile, other insiders)
25-Jul-164,801,638  Indirect
Corvus Pharmaceuticals, Inc.
Director
NasdaqGM:CRVS
(historical quotes, profile, other insiders)
24-Jun-165,379,349  Indirect
Dimension Therapeutics, Inc.
Director
NasdaqGS:DMTX
(historical quotes, profile, other insiders)
27-Oct-155,397,698  Indirect
ProNAi Therapeutics, Inc.
Director
NasdaqGM:DNAI
(historical quotes, profile, other insiders)
21-Jul-151,989,949  Indirect
Glaukos Corporation Common Stoc
Director
NYSE:GKOS
(historical quotes, profile, other insiders)
12-Aug-162,180,000  Indirect
Intercept Pharmaceuticals, Inc.
Director
NasdaqGS:ICPT
(historical quotes, profile, other insiders)
17-Jul-151,120,609  Indirect
Loxo Oncology, Inc.
Director
NasdaqGM:LOXO
(historical quotes, profile, other insiders)
10-Aug-161,728,000  Indirect
Mirati Therapeutics, Inc.
Beneficial Owner (10% or more)
NasdaqCM:MRTX
(historical quotes, profile, other insiders)
3-Feb-151,267,000  Indirect
Intellia Therapeutics, Inc.
Director
NasdaqGM:NTLA
(historical quotes, profile, other insiders)
11-May-165,265,826  Indirect
Otonomy, Inc.
Director
NasdaqGS:OTIC
(historical quotes, profile, other insiders)
30-Nov-151,850,094  Indirect
Pieris Pharmaceuticals, Inc.
Director
NasdaqCM:PIRS
(historical quotes, profile, other insiders)
6-Jul-157,259,620  Indirect
RESPONSE BIOMEDICA COM NPV
Director
OTC BB:RPBIF
(historical quotes, profile, other insiders)
16-Jun-165,788,459  Indirect
Selecta Biosciences, Inc.
Director
NasdaqGM:SELB
(historical quotes, other insiders)
27-Jun-161,842,797  Indirect
Sientra, Inc.
Beneficial Owner (10% or more)
NasdaqGS:SIEN
(historical quotes, profile, other insiders)
12-Oct-151,785,002  Indirect
SteadyMed Ltd. - Ordinary Share
Beneficial Owner (10% or more)
NasdaqGM:STDY
(historical quotes, profile, other insiders)
4-Aug-163,072,196  Indirect
ViewRay, Inc.
Director
NasdaqGM:VRAY
(historical quotes, profile, other insiders)
22-Aug-169,127,990  Indirect

Insider & restricted shareholder transactions reported over the last two years
DateSharesStockTransaction
22-Aug-16 *1,138,074VRAY Purchase at $2.95 - $2.95 per share.
(Cost of about $3,357,000)
12-Aug-16 *14,100GKOS Sale at $33.72 - $33.72 per share.
(Proceeds of about $475,000)
11-Aug-16 *160,900GKOS Sale at $33.63 - $33.63 per share.
(Proceeds of about $5,411,000)
10-Aug-16 *447,857LOXO Sale at $26.96 - $26.96 per share.
(Proceeds of about $12,074,000)
10-Aug-16 *117,938GKOS Sale at $33.77 - $33.77 per share.
(Proceeds of about $3,983,000)
4-Aug-16 *3,072,196STDY Statement of Ownership
3-Aug-16 *425,000GKOS Sale at $30.59 - $30.59 per share.
(Proceeds of about $13,001,000)
25-Jul-16 *33,334BOLD Purchase at $15 - $15 per share.
(Cost of about $500,000)
25-Jul-16 *4,544,066BOLD Acquisition (Non Open Market)
19-Jul-16 *224,238BOLD Statement of Ownership
27-Jun-16 *1,177,995SELB Acquisition (Non Open Market) at $0 per share.
27-Jun-16 *1,177,995SELB Acquisition (Non Open Market) at $0 per share.
27-Jun-16 *550,000SELB Purchase at $14 - $14 per share.
(Cost of about $7,700,000)
27-Jun-16 *550,000SELB Purchase at $14 - $14 per share.
(Cost of about $7,700,000)
24-Jun-16 *900CRVS Purchase at $12.99 - $12.99 per share.
(Cost of about $12,000)
23-Jun-16 *100CRVS Purchase at $12.92 - $12.92 per share.
(Cost of about $1,292)
21-Jun-16 *26,083CRVS Purchase at $12.87 - $12.87 per share.
(Cost of about $336,000)
21-Jun-16 *114,802SELB Statement of Ownership
17-Jun-16 *12,300CRVS Purchase at $12.48 - $12.48 per share.
(Cost of about $154,000)
16-Jun-16 *5,000CRVS Purchase at $12.04 - $12.04 per share.
(Cost of about $60,000)
16-Jun-16 *892,858RPBIF Purchase at $0.56 - $0.56 per share.
(Cost of about $500,000)
15-Jun-16 *5,000CRVS Purchase at $11.94 - $11.94 per share.
(Cost of about $60,000)
14-Jun-16 *10,000CRVS Purchase at $12.71 - $12.71 per share.
(Cost of about $127,000)
10-Jun-16 *20,000CRVS Purchase at $12.98 - $12.98 per share.
(Cost of about $260,000)
9-Jun-16 *30,000CRVS Purchase at $12.95 - $12.95 per share.
(Cost of about $389,000)
24-May-16 *518,400ADAP Purchase at $10.48 - $10.48 per share.
(Cost of about $5,433,000)
23-May-16 *1,191,600ADAP Purchase at $10.40 - $10.4 per share.
(Cost of about $12,393,000)
20-May-16 *4,716CRVS Purchase at $13.09 - $13.09 per share.
(Cost of about $62,000)
20-May-16 *2,400ADAP Purchase at $10.04 - $10.04 per share.
(Cost of about $24,000)
19-May-16 *2,600CRVS Purchase at $12.11 - $12.75 per share.
(Cost of about $32,000)
18-May-16 *4,200CRVS Purchase at $11.55 - $11.55 per share.
(Cost of about $49,000)
11-May-16 *250,000NTLA Purchase at $18 - $18 per share.
(Cost of about $4,500,000)
11-May-16 *2,412,180NTLA Acquisition (Non Open Market)
12-Apr-16 *1,360,224AGLE Statement of Ownership
30-Mar-16 *7,989,916VRAY Statement of Ownership
29-Mar-16 *4,708,450CRVS Acquisition (Non Open Market)
29-Mar-16 *550,000CRVS Purchase at $15 - $15 per share.
(Cost of about $8,250,000)
1-Jan-16 *2,632,704ADAP Statement of Ownership
30-Nov-15 *3,306OTIC Sale at $28.64 - $29.22 per share.
(Proceeds of about $96,000)
27-Nov-15 *29,000OTIC Sale at $28.97 - $28.97 per share.
(Proceeds of about $840,000)
25-Nov-15 *34,800OTIC Sale at $28.91 - $28.91 per share.
(Proceeds of about $1,006,000)
24-Nov-15 *36,100OTIC Sale at $28.75 - $28.75 per share.
(Proceeds of about $1,038,000)
23-Nov-15 *80,800OTIC Sale at $28.45 - $28.45 per share.
(Proceeds of about $2,299,000)
20-Nov-15 *83,900OTIC Sale at $28.59 - $28.59 per share.
(Proceeds of about $2,399,000)
19-Nov-15 *127,300OTIC Sale at $28.60 - $28.6 per share.
(Proceeds of about $3,641,000)
17-Nov-15 *11,098OTIC Sale at $28.80 - $29.09 per share.
(Proceeds of about $321,000)
27-Oct-15 *5,197,698DMTX Acquisition (Non Open Market)
27-Oct-15 *200,000DMTX Purchase at $13 - $13 per share.
(Cost of about $2,600,000)
12-Oct-15 *287,891SIEN Sale at $5.98 - $5.98 per share.
(Proceeds of about $1,722,000)
9-Oct-15 *212,709SIEN Sale at $7.03 - $7.03 per share.
(Proceeds of about $1,495,000)
8-Oct-15 *400,000SIEN Sale at $7.24 - $7.24 per share.
(Proceeds of about $2,896,000)
7-Oct-15 *53,900SIEN Sale at $7.36 - $7.36 per share.
(Proceeds of about $397,000)
6-Oct-15 *7,000SIEN Sale at $7.80 - $7.8 per share.
(Proceeds of about $55,000)
5-Oct-15 *138,100SIEN Sale at $8.19 - $8.19 per share.
(Proceeds of about $1,131,000)
2-Oct-15 *47,900SIEN Sale at $10.34 - $10.34 per share.
(Proceeds of about $495,000)
1-Oct-15 *47,500SIEN Sale at $10.34 - $10.34 per share.
(Proceeds of about $491,000)
30-Sep-15 *43,840SIEN Sale at $10.17 - $10.17 per share.
(Proceeds of about $446,000)
29-Sep-15 *10,558SIEN Sale at $10.08 - $10.08 per share.
(Proceeds of about $106,000)
28-Sep-15 *10,602SIEN Sale at $10.30 - $10.3 per share.
(Proceeds of about $109,000)
25-Sep-15 *132,000SIEN Sale at $10.07 - $11.07 per share.
(Proceeds of about $1,395,000)
24-Sep-15 *8,306SIEN Sale at $9.78 - $11 per share.
(Proceeds of about $86,000)
21-Jul-15 *175,000DNAI Purchase at $17 - $17 per share.
(Cost of about $2,975,000)
21-Jul-15 *1,814,949DNAI Acquisition (Non Open Market) at $5.22 - $5.22 per share.
(Value of about $9,474,000)
17-Jul-15 *285ICPT Acquisition (Non Open Market)
6-Jul-15 *500,000PIRS Purchase at $2.75 - $2.75 per share.
(Cost of about $1,375,000)
30-Jun-15 *2,882,064GKOS Acquisition (Non Open Market)
30-Jun-15 *27,607GKOS Option Exercise
30-Jun-15 *11,734GKOS Disposition (Non Open Market) at $18 - $18 per share.
(Value of about $211,000)
29-Jun-15 *6,759,620PIRS Statement of Ownership
26-Mar-15 *157,200ICPT Sale at $281.11 - $294.82 per share.
(Proceeds of about $45,268,000)
25-Mar-15 *2,800ICPT Sale at $270.23 - $270.23 per share.
(Proceeds of about $757,000)
24-Mar-15 *45,600ICPT Sale at $268.13 - $275.56 per share.
(Proceeds of about $12,396,000)
23-Mar-15 *159,400ICPT Sale at $270.70 - $288.6 per share.
(Proceeds of about $44,576,000)
3-Feb-15 *100,000MRTX Purchase at $20 - $20 per share.
(Cost of about $2,000,000)
    * Indicates that some (or all) shares are held indirectly (e.g. in a trust, by a spouse, etc.)



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