Insider Trades - WYSENSKI NANCY

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WYSENSKI NANCY: Declared Holdings
Company/Relationship	Reported	Shares	Ownership
Vertex Pharmaceuticals Incorpor Officer NasdaqGS:VRTX (historical quotes, profile, SEC, other insiders)	14-May-12	32,232	Direct

Insider & restricted shareholder transactions reported over the last two years
Date Shares Stock Transaction
14-May-12 180,000 VRTX Option Exercise at $37.86 - $39.7 per share.
(Cost of about $6,980,000)
14-May-12 180,000 VRTX Automatic Sale at $64.27 - $65 per share.
(Proceeds of about $11,634,000)
8-May-12 38,009 VRTX Option Exercise at $33.82 - $39.7 per share.
(Cost of about $1,397,000)
8-May-12 38,009 VRTX Automatic Sale at $59.19 - $63.52 per share.
(Proceeds of about $2,332,000)
7-May-12 142,695 VRTX Option Exercise at $33.82 - $39.7 per share.
(Cost of about $5,245,000)
7-May-12 147,695 VRTX Automatic Sale at $54.50 per share.
(Proceeds of $8,049,377)
2-Feb-12 14,501 VRTX Acquisition (Non Open Market) at $0.01 per share.
(Value of $145)
19-Jan-12 6,042 VRTX Automatic Sale at $37 per share.
(Proceeds of $223,554)
12-Dec-11 5,000 VRTX Automatic Sale at $28.90 per share.
(Proceeds of $144,500)
15-Nov-11 606 VRTX Automatic Sale at $29.77 per share.
(Proceeds of $18,040)

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Insider & restricted shareholder transactions reported over the last two years
Date	Shares	Stock	Transaction
14-May-12	180,000	VRTX	Option Exercise at $37.86 - $39.7 per share. (Cost of about $6,980,000)
14-May-12	180,000	VRTX	Automatic Sale at $64.27 - $65 per share. (Proceeds of about $11,634,000)
8-May-12	38,009	VRTX	Option Exercise at $33.82 - $39.7 per share. (Cost of about $1,397,000)
8-May-12	38,009	VRTX	Automatic Sale at $59.19 - $63.52 per share. (Proceeds of about $2,332,000)
7-May-12	142,695	VRTX	Option Exercise at $33.82 - $39.7 per share. (Cost of about $5,245,000)
7-May-12	147,695	VRTX	Automatic Sale at $54.50 per share. (Proceeds of $8,049,377)
2-Feb-12	14,501	VRTX	Acquisition (Non Open Market) at $0.01 per share. (Value of $145)
19-Jan-12	6,042	VRTX	Automatic Sale at $37 per share. (Proceeds of $223,554)
12-Dec-11	5,000	VRTX	Automatic Sale at $28.90 per share. (Proceeds of $144,500)
15-Nov-11	606	VRTX	Automatic Sale at $29.77 per share. (Proceeds of $18,040)