Insider Trades - RUBIN STEVEN D

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RUBIN STEVEN D: Declared Holdings
Company/Relationship	Reported	Shares	Ownership
NON INVASIVE MONITORNG SYS NEW Director OTC BB:NIMU.OB (historical quotes, profile, SEC, other insiders)	30-Oct-08	0	Direct
OPKO HEALTH INC. Officer AMEX:OPK (historical quotes, profile, other insiders)	8-May-08	4,189,168	Direct
MODIGENE INC Director OTC BB:PBTH.OB (historical quotes, other insiders)	4-Mar-08	27,666	Direct
CASTLE BRANDS INC. Director AMEX:ROX (historical quotes, profile, other insiders)	21-Jan-09	1,000	Direct

Insider & restricted shareholder transactions reported over the last two years
Date Shares Stock Transaction
21-Jan-09 1,000 ROX Statement of Ownership
30-Oct-08 0 NIMU.OB Statement of Ownership
8-May-08 20,000 OPK Purchase at $1.25 per share.
(Cost of $25,000)
4-Mar-08 27,666 PBTH.OB Statement of Ownership
13-Feb-08 10,000 OPK Purchase at $1.80 per share.
(Cost of $18,000)

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Insider & restricted shareholder transactions reported over the last two years
Date	Shares	Stock	Transaction
21-Jan-09	1,000	ROX	Statement of Ownership
30-Oct-08	0	NIMU.OB	Statement of Ownership
8-May-08	20,000	OPK	Purchase at $1.25 per share. (Cost of $25,000)
4-Mar-08	27,666	PBTH.OB	Statement of Ownership
13-Feb-08	10,000	OPK	Purchase at $1.80 per share. (Cost of $18,000)