Insider Trades - GEARY RICHARD S

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GEARY RICHARD S: Declared Holdings
Company/Relationship	Reported	Shares	Ownership
Isis Pharmaceuticals, Inc. Officer NasdaqGM:ISIS (historical quotes, profile, other insiders)	2-Jul-09	0	Direct

Insider & restricted shareholder transactions reported over the last two years
Date Shares Stock Transaction
2-Jul-09 387 ISIS Automatic Sale at $15.89 per share.
(Proceeds of $6,149)
1-Jul-09 387 ISIS Acquisition (Non Open Market) at $12.30 per share.
(Value of $4,760)
2-Jan-09 1,415 ISIS Automatic Sale at $14.05 per share.
(Proceeds of $19,880)
1-Jan-09 1,415 ISIS Acquisition (Non Open Market) at $11.65 per share.
(Value of $16,484)
16-Aug-08 0 ISIS Statement of Ownership

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Insider & restricted shareholder transactions reported over the last two years
Date	Shares	Stock	Transaction
2-Jul-09	387	ISIS	Automatic Sale at $15.89 per share. (Proceeds of $6,149)
1-Jul-09	387	ISIS	Acquisition (Non Open Market) at $12.30 per share. (Value of $4,760)
2-Jan-09	1,415	ISIS	Automatic Sale at $14.05 per share. (Proceeds of $19,880)
1-Jan-09	1,415	ISIS	Acquisition (Non Open Market) at $11.65 per share. (Value of $16,484)
16-Aug-08	0	ISIS	Statement of Ownership