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Insider Filings - CROOKE STANLEY T
Last Updated 
18-Aug-14
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CROOKE STANLEY T: Declared Holdings
Company/RelationshipReportedShares  Ownership
Isis Pharmaceuticals, Inc.
Officer
NasdaqGS:ISIS
(historical quotes, profile, other insiders)
13-Aug-14
13-Aug-14
6,941
   627
7,568
  Direct
  Indirect  
  Total

Insider & restricted shareholder transactions reported over the last two years
DateSharesStockTransaction
13-Aug-14 *1,600ISIS Option Exercise at $11.27 per share.
(Cost of $18,032)
13-Aug-14 15,500ISIS Option Exercise at $14.47 per share.
(Cost of $224,285)
13-Aug-14 *1,600ISIS Automatic Sale at $35.45 per share.
(Proceeds of $56,720)
13-Aug-14 15,500ISIS Automatic Sale at $35.45 per share.
(Proceeds of $549,475)
1-Aug-14 15,000ISIS Option Exercise at $14.47 per share.
(Cost of $217,050)
1-Aug-14 *1,000ISIS Option Exercise at $11.27 per share.
(Cost of $11,270)
1-Aug-14 15,000ISIS Automatic Sale at $30.53 per share.
(Proceeds of $457,950)
1-Aug-14 *1,000ISIS Automatic Sale at $30.53 per share.
(Proceeds of $30,530)
1-Jul-14 *2,000ISIS Automatic Sale at $35.55 per share.
(Proceeds of $71,100)
1-Jul-14 15,500ISIS Automatic Sale at $35.58 per share.
(Proceeds of $551,490)
1-Jul-14 *2,000ISIS Option Exercise at $11.27 - $14.47 per share.
1-Jul-14 15,500ISIS Option Exercise at $14.47 per share.
(Cost of $224,285)
19-Jun-14 11,000ISIS Option Exercise at $14.47 per share.
(Cost of $159,170)
19-Jun-14 11,000ISIS Automatic Sale at $35.10 per share.
(Proceeds of $386,100)
10-Jun-14 *1,000ISIS Automatic Sale at $33.46 per share.
(Proceeds of $33,460)
10-Jun-14 10,000ISIS Automatic Sale at $33.46 per share.
(Proceeds of $334,600)
10-Jun-14 *1,000ISIS Option Exercise at $14.47 per share.
(Cost of $14,470)
10-Jun-14 10,000ISIS Option Exercise at $14.47 per share.
(Cost of $144,700)
2-Apr-14 7,000ISIS Option Exercise at $14.47 per share.
(Cost of $101,290)
2-Apr-14 *1,800ISIS Option Exercise at $14.47 per share.
(Cost of $26,046)
2-Apr-14 7,000ISIS Automatic Sale at $43.65 per share.
(Proceeds of $305,550)
2-Apr-14 *1,800ISIS Automatic Sale at $43.65 per share.
(Proceeds of $78,570)
16-Jan-14 *281ISIS Sale at $47.08 per share.
(Proceeds of $13,229)
16-Jan-14 3,246ISIS Sale at $47.08 per share.
(Proceeds of $152,821)
15-Jan-14 *734ISIS Option Exercise at $0 per share.
15-Jan-14 8,526ISIS Option Exercise at $0 per share.
8-Jan-14 11,000ISIS Option Exercise at $14.47 per share.
(Cost of $159,170)
8-Jan-14 *1,500ISIS Option Exercise at $14.47 per share.
(Cost of $21,705)
8-Jan-14 11,000ISIS Automatic Sale at $40.05 per share.
(Proceeds of $440,549)
8-Jan-14 *1,500ISIS Automatic Sale at $40.05 per share.
(Proceeds of $60,074)
2-Jan-14 *2,500ISIS Automatic Sale at $39.25 per share.
(Proceeds of $98,125)
2-Jan-14 29,000ISIS Automatic Sale at $39.25 - $40 per share.
(Proceeds of about $1,149,000)
2-Jan-14 *2,500ISIS Option Exercise at $14.47 per share.
(Cost of $36,175)
2-Jan-14 29,000ISIS Option Exercise at $14.47 per share.
(Cost of $419,630)
20-Sep-13 8,740ISIS Option Exercise at $11.12 per share.
(Cost of $97,188)
20-Sep-13 8,740ISIS Automatic Sale at $35.90 per share.
(Proceeds of $313,766)
19-Sep-13 50,000ISIS Option Exercise at $11.12 per share.
(Cost of $556,000)
19-Sep-13 50,000ISIS Automatic Sale at $35.02 - $35.12 per share.
(Proceeds of about $1,754,000)
11-Sep-13 *20,000ISIS Automatic Sale at $31.18 per share.
(Proceeds of $623,600)
10-Sep-13 *30,000ISIS Automatic Sale at $31.65 per share.
(Proceeds of $949,500)
9-Sep-13 26,615ISIS Option Exercise at $11.12 per share.
(Cost of $295,958)
9-Sep-13 26,615ISIS Automatic Sale at $30.42 per share.
(Proceeds of $809,628)
23-Jul-13 11,500ISIS Automatic Sale at $30 per share.
(Proceeds of $345,000)
23-Jul-13 11,500ISIS Option Exercise at $11.12 per share.
(Cost of $127,879)
22-Jul-13 20,000ISIS Automatic Sale at $30.53 - $31.02 per share.
(Proceeds of about $616,000)
22-Jul-13 20,000ISIS Option Exercise at $11.12 - $15.38 per share.
19-Jul-13 22,200ISIS Automatic Sale at $30.19 - $31.4 per share.
(Proceeds of about $684,000)
19-Jul-13 22,200ISIS Option Exercise at $15.38 per share.
(Cost of $341,436)
18-Jul-13 20,000ISIS Option Exercise at $11.12 per share.
(Cost of $222,399)
18-Jul-13 20,000ISIS Automatic Sale at $30.02 - $30.2 per share.
(Proceeds of about $602,000)
17-Jul-13 *13,300ISIS Automatic Sale at $31.22 - $31.96 per share.
(Proceeds of about $420,000)
17-Jul-13 *13,300ISIS Option Exercise at $9.92 - $15.38 per share.
16-Jul-13 6,000ISIS Automatic Sale at $33.31 per share.
(Proceeds of $199,860)
16-Jul-13 6,000ISIS Option Exercise at $11.12 per share.
(Cost of $66,720)
15-Jul-13 30,000ISIS Option Exercise at $11.12 per share.
(Cost of $333,600)
15-Jul-13 30,000ISIS Automatic Sale at $33.57 - $34.05 per share.
(Proceeds of about $1,014,000)
12-Jul-13 30,000ISIS Automatic Sale at $32.83 - $33.5 per share.
(Proceeds of about $995,000)
12-Jul-13 30,000ISIS Option Exercise at $11.12 - $15.38 per share.
11-Jul-13 30,000ISIS Option Exercise at $15.38 per share.
(Cost of $461,400)
11-Jul-13 30,000ISIS Automatic Sale at $32 per share.
(Proceeds of $960,000)
10-Jul-13 30,000ISIS Automatic Sale at $30.05 per share.
(Proceeds of $901,500)
10-Jul-13 30,000ISIS Option Exercise at $15.38 per share.
(Cost of $461,400)
9-Jul-13 30,000ISIS Automatic Sale at $30.04 per share.
(Proceeds of $901,200)
9-Jul-13 30,000ISIS Option Exercise at $15.38 per share.
(Cost of $461,400)
8-Jul-13 54,992ISIS Automatic Sale at $15.38 - $30.09 per share.
8-Jul-13 5,008ISIS Option Exercise at $15.38 per share.
(Cost of $77,023)
5-Jul-13 24,180ISIS Option Exercise at $15.38 per share.
(Cost of $371,888)
5-Jul-13 24,180ISIS Automatic Sale at $30.02 per share.
(Proceeds of $725,883)
1-Jul-13 *10,000ISIS Automatic Sale at $28.17 per share.
(Proceeds of $281,700)
28-Jun-13 *10,683ISIS Automatic Sale at $27.31 per share.
(Proceeds of $291,752)
28-Jun-13 10,000ISIS Option Exercise at $6.81 per share.
(Cost of $68,100)
28-Jun-13 *10,683ISIS Option Exercise at $6.81 - $11.12 per share.
28-Jun-13 10,000ISIS Automatic Sale at $27.07 per share.
(Proceeds of $270,700)
27-Jun-13 20,000ISIS Option Exercise at $6.81 per share.
(Cost of $136,200)
27-Jun-13 20,000ISIS Automatic Sale at $27.40 - $28.3 per share.
(Proceeds of about $557,000)
26-Jun-13 *10,000ISIS Automatic Sale at $26.70 per share.
(Proceeds of $267,000)
26-Jun-13 20,000ISIS Automatic Sale at $27.10 per share.
(Proceeds of $542,000)
26-Jun-13 20,000ISIS Option Exercise at $6.81 per share.
(Cost of $136,200)
25-Jun-13 30,000ISIS Automatic Sale at $27.87 - $28.32 per share.
(Proceeds of about $843,000)
25-Jun-13 30,000ISIS Option Exercise at $6.81 per share.
(Cost of $204,300)
24-Jun-13 *30,000ISIS Automatic Sale at $25.16 - $25.22 per share.
(Proceeds of about $756,000)
24-Apr-13 *10,000ISIS Automatic Sale at $22.12 per share.
(Proceeds of $221,200)
23-Apr-13 *30,000ISIS Sale at $22.10 per share.
(Proceeds of $663,000)
22-Apr-13 20,000ISIS Automatic Sale at $20.99 per share.
(Proceeds of $419,799)
22-Apr-13 20,000ISIS Option Exercise at $7.26 per share.
(Cost of $145,200)
22-Apr-13 *10,000ISIS Automatic Sale at $20.99 per share.
(Proceeds of $209,899)
19-Apr-13 30,000ISIS Option Exercise at $7.26 per share.
(Cost of $217,800)
19-Apr-13 30,000ISIS Automatic Sale at $20.01 per share.
(Proceeds of $600,300)
16-Jan-13 *143ISIS Sale at $14 per share.
(Proceeds of $2,002)
16-Jan-13 1,317ISIS Sale at $14 per share.
(Proceeds of $18,438)
15-Jan-13 *317ISIS Option Exercise at $0 per share.
15-Jan-13 2,978ISIS Option Exercise at $0 per share.
21-Sep-12 29,462ISIS Automatic Sale at $14.06 per share.
(Proceeds of $414,235)
21-Sep-12 29,462ISIS Option Exercise at $6.84 per share.
(Cost of $201,520)
20-Sep-12 30,000ISIS Option Exercise at $5.25 - $6.84 per share.
20-Sep-12 30,000ISIS Automatic Sale at $15.01 per share.
(Proceeds of $450,300)
19-Sep-12 30,000ISIS Option Exercise at $5.25 per share.
(Cost of $157,500)
19-Sep-12 30,000ISIS Automatic Sale at $14.82 per share.
(Proceeds of $444,600)
13-Sep-12 27,074ISIS Automatic Sale at $14.55 per share.
(Proceeds of $393,926)
13-Sep-12 27,074ISIS Option Exercise at $5.25 per share.
(Cost of $142,138)
6-Sep-12 17,388ISIS Option Exercise at $5.25 per share.
(Cost of $91,287)
6-Sep-12 *12,612ISIS Option Exercise at $5.25 - $6.84 per share.
6-Sep-12 *12,612ISIS Automatic Sale at $15 - $15.04 per share.
(Proceeds of about $189,000)
6-Sep-12 17,388ISIS Automatic Sale at $15 - $15.04 per share.
(Proceeds of about $261,000)
5-Sep-12 15,000ISIS Option Exercise at $5.25 per share.
(Cost of $78,750)
5-Sep-12 15,000ISIS Automatic Sale at $14.82 per share.
(Proceeds of $222,300)
4-Sep-12 30,000ISIS Automatic Sale at $14.11 per share.
(Proceeds of $423,300)
4-Sep-12 30,000ISIS Option Exercise at $5.25 per share.
(Cost of $157,500)
    * Indicates that some (or all) shares are held indirectly (e.g. in a trust, by a spouse, etc.)



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