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Insider Filings - PARSHALL B LYNNE
Last Updated 
29-Apr-13
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PARSHALL B LYNNE: Declared Holdings
Company/RelationshipReportedShares  Ownership
Isis Pharmaceuticals, Inc.
Officer
NasdaqGS:ISIS
(historical quotes, profile, other insiders) 		25-Apr-13
23-Apr-13		2,941
   0
2,941		  Direct
  Indirect  
  Total

Insider & restricted shareholder transactions reported over the last two years
DateSharesStockTransaction
25-Apr-13 25,854ISIS Option Exercise at $6.81 - $11.12 per share.
25-Apr-13 25,854ISIS Automatic Sale at $22.50 per share.
(Proceeds of $581,715)
24-Apr-13 30,000ISIS Option Exercise at $11.12 per share.
(Cost of $333,600)
24-Apr-13 30,000ISIS Automatic Sale at $22.12 per share.
(Proceeds of $663,600)
23-Apr-13 *20,000ISIS Sale at $22.10 per share.
(Proceeds of $442,000)
23-Apr-13 10,000ISIS Option Exercise at $11.12 per share.
(Cost of $111,199)
23-Apr-13 *20,000ISIS Option Exercise at $6.81 per share.
(Cost of $136,200)
23-Apr-13 10,000ISIS Sale at $22.10 per share.
(Proceeds of $221,000)
22-Apr-13 30,000ISIS Option Exercise at $11.12 per share.
(Cost of $333,600)
22-Apr-13 30,000ISIS Automatic Sale at $20.99 per share.
(Proceeds of $629,700)
19-Apr-13 30,000ISIS Automatic Sale at $20.01 per share.
(Proceeds of $600,300)
19-Apr-13 30,000ISIS Option Exercise at $7.26 per share.
(Cost of $217,800)
16-Jan-13 759ISIS Sale at $14 per share.
(Proceeds of $10,626)
15-Jan-13 1,715ISIS Option Exercise at $0 per share.
7-Sep-12 *10,000ISIS Option Exercise at $6.84 per share.
(Cost of $68,400)
7-Sep-12 2,506ISIS Option Exercise at $6.84 per share.
(Cost of $17,141)
7-Sep-12 2,506ISIS Automatic Sale at $15.12 per share.
(Proceeds of $37,890)
7-Sep-12 *10,000ISIS Automatic Sale at $15.12 per share.
(Proceeds of $151,200)
6-Sep-12 *20,000ISIS Automatic Sale at $15 - $15.04 per share.
(Proceeds of about $300,000)
6-Sep-12 10,000ISIS Automatic Sale at $15 - $15.04 per share.
(Proceeds of about $150,000)
6-Sep-12 *20,000ISIS Option Exercise at $5.25 - $6.84 per share.
6-Sep-12 10,000ISIS Option Exercise at $5.25 - $6.84 per share.
5-Sep-12 2,000ISIS Option Exercise at $5.25 per share.
(Cost of $10,500)
5-Sep-12 2,000ISIS Automatic Sale at $15 per share.
(Proceeds of $30,000)
4-Sep-12 *20,000ISIS Option Exercise at $5.25 per share.
(Cost of $105,000)
4-Sep-12 10,000ISIS Option Exercise at $5.25 per share.
(Cost of $52,500)
4-Sep-12 10,000ISIS Automatic Sale at $15 per share.
(Proceeds of $150,000)
4-Sep-12 *20,000ISIS Automatic Sale at $15 per share.
(Proceeds of $300,000)
21-Dec-11 2,363ISIS Option Exercise at $5.80 per share.
(Cost of $13,705)
21-Dec-11 *4,400ISIS Option Exercise at $5.80 per share.
(Cost of $25,520)
21-Dec-11 2,363ISIS Automatic Sale at $6.92 per share.
(Proceeds of $16,351)
21-Dec-11 *4,400ISIS Automatic Sale at $6.92 per share.
(Proceeds of $30,448)
20-Dec-11 3,600ISIS Option Exercise at $5.80 per share.
(Cost of $20,880)
20-Dec-11 *7,000ISIS Option Exercise at $5.80 per share.
(Cost of $40,600)
20-Dec-11 3,600ISIS Automatic Sale at $6.82 - $6.92 per share.
(Proceeds of about $25,000)
20-Dec-11 *7,000ISIS Automatic Sale at $6.82 - $6.92 per share.
(Proceeds of about $48,000)
19-Dec-11 *6,600ISIS Option Exercise at $5.80 - $580 per share.
19-Dec-11 2,300ISIS Option Exercise at $5.80 per share.
(Cost of $13,340)
19-Dec-11 2,300ISIS Automatic Sale at $6.82 - $6.9 per share.
(Proceeds of about $16,000)
19-Dec-11 *4,600ISIS Automatic Sale at $6.82 - $6.9 per share.
(Proceeds of about $32,000)
16-Dec-11 *4,000ISIS Automatic Sale at $6.79 per share.
(Proceeds of $27,160)
16-Dec-11 2,000ISIS Option Exercise at $5.80 per share.
(Cost of $11,600)
16-Dec-11 *2,000ISIS Option Exercise at $5.80 per share.
(Cost of $11,600)
16-Dec-11 2,000ISIS Automatic Sale at $6.79 per share.
(Proceeds of $13,580)
    * Indicates that some (or all) shares are held indirectly (e.g. in a trust, by a spouse, etc.)

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