PARIS--(MARKET WIRE)--Aug 22, 2008 -- BioAlliance Pharma announces the grant of its main patent on the Lauriad® technology in Europe

The patent has been validated in the main European countries and the opposition period has now expired.

Paris, August 22, 2008 - BioAlliance Pharma SA (Euronext Paris: FR0010095596-BIO),

the specialty pharmaceutical company focused on the treatment of opportunistic infections in cancer

and HIV, today announced the grant of its main patent on the Lauriad® technology in Europe.

The patent describes and protects a muco-adhesive tablet for various applications in the field of opportunistic infections associated with AIDS and cancer. It has been validated in the main European countries and the opposition period has now expired.

"The grant of this patent acknowledges the true innovation behind the Lauriad® muco-adhesive technology", stated Dominique Costantini, President and CEO of BioAlliance Pharma. "It reinforces our positioning in the target markets for the Lauriad® technology: oropharyngeal candidiasis, labial herpes and chronic pain".

Given BioAlliance Pharma's commitment to the development and commercialization of innovative products, intellectual property (IP) is at the heart of the company's business activity. The company is developing a pro-active IP strategy that is tightly coupled to its R&D projects.

BioAlliance Pharma's patent portfolio now encompasses 25 published patent families (comprising 196 patent applications and granted patents) covering innovative technologies or products in the fields of opportunistic infections, cancer and AIDS. More than half the portfolio is made up of granted patents.

About BioAlliance Pharma

BioAlliance Pharma SA is a specialty pharmaceutical company focused on the treatment of opportunistic infections in cancer and HIV. The company develops and commercializes innovative products which address drug resistance issues. BioAlliance Pharma has launched its first portfolio product (Loramyc®) in France and, more recently, in the UK, Germany and Denmark, and has already received European Marketing Authorizations in Belgium and Luxemburg. The product has also completed a pivotal Phase III clinical trial in the United States in oropharyngeal candidiasis. The company is also performing a Phase III trial in labial herpes with acyclovir Lauriad® (which is based on the same Lauriad® muco-adhesive technology as Loramyc®, enabling targeted release at the disease site). BioAlliance Pharma also has a second technology (the Transdrug® nanoparticle technology, designed specifically for intracellular targeting) and, furthermore, is developing a new therapeutic entities program in oncology and infectious disease. BioAlliance Pharma has established several strategic alliances for commercializing Loramyc®, with agreements in 2007 for Europe (with the SpeBio joint venture) and the United States (with Par Pharmaceutical) and in 2008 for Asia (Korea, Malaysia, Singapore and Taiwan with Handok Pharmaceuticals and then China with Novamed). In May and August 2008, the company expanded its product portfolio by acquiring the Europe commercial rights to, respectively, ondansetron Oral Spray (OS) from NovaDel Pharma Inc. (NVD - News) and ondansetron RapidFilmTM from APR/Labtec. For more information, visit BioAlliance Pharma's website at www.bioalliancepharma.com.

Disclaimer

This communication expressly or implicitly contains certain forward-looking statements concerning BioAlliance Pharma SA and its business. Such statements involve certain known and unknown risks, uncertainties and other factors, which could cause the actual results, financial condition, performance or achievements of BioAlliance Pharma SA to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. BioAlliance Pharma SA is providing this communication as of this date and does not undertake to update any forward-looking statements contained herein as a result of new information, future events or otherwise. For a discussion of risks and uncertainties which could cause actual results, financial condition, performance or achievements of BioAlliance Pharma SA to differ from those contained in the forward-looking statements, please refer to the Risk Factors ("Facteurs de Risque") section of the reference document approved by the AMF on April 11 2008 under the number R. 08-021, which is available on the AMF website (http://www.amf-france.org) or on BioAlliance Pharma S.A.'s website (http://www.bioalliancepharma.com).

This information is provided by HUGIN

     BioAlliance Pharma SA
     Dominique Costantini
     President and CEO
     Tel.: +33 1 45 58 76 01
     Email Contact
      
     Nicolas Fellmann
     CFO
     Tel.: +33 1 45 58 71 00
     Email Contact
      
     ALIZE RP
     Caroline Carmagnol
     Tel.: +33 6 64 18 99 59
     Email Contact