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RGLS > SEC Filings for RGLS > Form 8-K on 7-Aug-2013All Recent SEC Filings

Show all filings for REGULUS THERAPEUTICS INC.



Entry into a Material Definitive Agreement, Financial Statements and Ex

Item 1.01 Entry into a Material Definitive Agreement.

On August 2, 2013, Regulus Therapeutics Inc. (the "Company") entered into an Amendment ("Amendment") to the Amended and Restated License and Collaboration Agreement with Isis Pharmaceuticals, Inc. and Alnylam Pharmaceuticals, Inc. ("Alnylam") dated January 1, 2009, as amended in June 2010 and October 2011. Pursuant to the terms of the Amendment, the Company will have a license to use certain Alnylam-controlled intellectual property concerning the use and manufacture of GalNac conjugates ("GalNac Process Technology") on a non-exclusive basis. The Company will generally not be permitted to sublicense or otherwise transfer the GalNac Process Technology or any of the Alnylam licensed intellectual property rights relating to GalNac conjugate technology that are not GalNac Process Technology without the prior written consent of Alnylam, subject to certain limited exceptions for sublicenses to third party collaboration partners.

The foregoing description of the Amendment is qualified in its entirety by reference to the Amendment, a copy of which is attached as Exhibit 99.1 to this Current Report on Form 8-K and incorporated by reference herein.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits.

Number                                   Description

99.1       Amendment Number Three to the Amended and Restated License and
            Collaboration Agreement among the Company, Alnylam Pharmaceuticals,
            Inc. and Isis Pharmaceuticals, Inc., dated August 2, 2013.

Confidential treatment has been requested for certain portions of this exhibit, which portions have been omitted and filed separately with the Securities and Exchange Commission.

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