On January 26, 2013, Delcath Systems, Inc. (the "Company") entered into a First Amendment to Research and Distribution Agreement (the "Amendment") to the Research and Distribution Agreement with CHI-FU Trading Co., Ltd. dated February 9, 2010 (the "Agreement"). The Amendment incorporates various changes to the Agreement, including but not limited to the following: (1) amending the brand name of the Company's device to the currently used "Delcath Hepatic CHEMOSTAT® Delivery System" name; (2) clarifying that the Company will create the research protocols and have the right to make in person visits to the research locations; (3) amending the timing of the expected receipt of certain regulatory approvals, as well as the timing of milestone payments;
(4) incorporating a new requirement that end-users complete training courses;
(5) extending the time period for CHI-FU Trading Co., Ltd. to exercise its option to gain distribution rights in Singapore; and (6) allowing CHI-FU Trading Co., Ltd. to appoint sub-distributors and dealers.

The foregoing description of the Amendment is not complete and is qualified in its entirety by reference to the full text of the Amendment, a copy of which is filed herewith as Exhibit 10.1 to this Current Report on Form 8-K and is incorporated herein by reference, as well as to the full text of the Agreement, which was filed with the Company's Form 10-Q on May 5, 2010, and is incorporated herein by reference.

(d) Exhibits

Exhibit
Number                                    Description

10.1         First Amendment to Research and Distribution Agreement between Delcath
             Systems, Inc. and CHI-FU Trading Co., Ltd., dated January 26, 2013.