Medgenics, Inc. is filing the company overview attached as Exhibit 99.1 for the purpose of updating certain aspects of its publicly disclosed descriptions of its business, and the risk factors attached as Exhibit 99.2 for the purpose of updating the risk factor disclosure contained in its public filings, including those discussed under the caption "Risk Factors" in its Annual Report on Form 10-K for the year ended December 31, 2011 and its Quarterly Report on Form 10-Q for the three month period ended September 30, 2012, which were filed with the Securities and Exchange Commission on March 6, 2012 and November 14, 2012, respectively.

(d) Exhibits. The following exhibit is furnished herewith:

Exhibit No.   Description

99.1          Company Overview
99.2          Risk Factors