Item 8.01 Other Events.

On January 3, 2013, Synergy Pharmaceuticals Inc. (the "Company") commenced its Annual Meeting of Shareholders (the "Annual Meeting") as previously scheduled and adjourned the meeting until Monday, January 14, 2013, at 10:00 a.m., Eastern Standard Time. The Annual Meeting was adjourned to allow the Company's stockholders a reasonable amount of time to consider the information about the Company's results from its Phase IIb/III clinical study.

The reconvened Annual Meeting will be held at the offices of Sichenzia Ross Friedman Ference LLP, 61 Broadway, 32nd Floor, New York, NY 10006. Shareholders who have already voted do not need to recast their votes. Proxies previously submitted in respect of the meeting will be voted at the adjourned meeting unless properly revoked. Given the adjournment, proxies may now be received by our registrar and transfer agent, Philadelphia Stock Transfer Inc., no later than January 13, 2013 at 11:59 p.m. (Eastern Standard Time).

A copy of the press release announcing the adjournment of the Annual Meeting is attached hereto as Exhibit 99.1.

Item 9.01 Financial Statements and Exhibits.

The following exhibits are furnished as part of this Current Report on Form 8-K:

(d) Exhibits.

99.1 Press Release, dated January 3, 2013.