Revised Risk Factors

The Company is filing the risk factors attached hereto as Exhibit 99.1 for the purpose of updating and superseding the risk factor disclosure contained in its public filings, including those discussed under the caption "Risk Factors" in its Annual Report on Form 10-K for the year ended December 31, 2011, which was filed with the SEC on March 13, 2012 and its Quarterly Report on Form 10-Q for the period ended September 30, 2012, which was filed with the SEC on November 6, 2012.

Retrospective Reporting of Additional Information in response to Adoption of New Accounting Standard

The Company is also filing this Current Report on Form 8-K to disclose the impact of the adoption of a new accounting standard (ASU No. 2011-05, as amended by ASU No. 2011-12) on its historical financial statements in the Company's most recent Annual Report on Form 10-K. ASU No. 2011-05, which the Company adopted beginning with its fiscal quarter ended March 31, 2012, requires, among other things, that the Company retrospectively report additional information related to the presentation of total comprehensive income (loss), namely net loss, the components of other comprehensive income (loss) and total comprehensive loss on the face of the financial statements, either in a single continuous statement of comprehensive income (loss) or in two separate but consecutive statements. The following table presents selected components of the Consolidated Statements of Comprehensive Income (loss) for the Company for each of the three years ended December 31, 2011, 2010 and 2009 and should be read in conjunction with the Company's 2011 Annual Report on Form 10-K, which previously included this information in the Consolidated Statements of Stockholders' Equity.

                                                             Years Ended December 31,
                                                      2011             2010             2009
Consolidated Statements of Comprehensive Income
(Loss)
Unaudited
(in thousands)
Net loss                                            $ (40,042 )      $ (48,984 )      $ (31,279 )
Other comprehensive income (loss):
Net unrealized holding gains (losses) on
available-for-sale securities arising during
the period                                          $     (32 )      $      17        $    (678 )

Comprehensive loss                                  $ (40,074 )      $ (48,967 )      $ (31,957 )

(d) The following exhibits are included in this report:

Exhibit No. Description

99.1 Risk Factors