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ANAC > SEC Filings for ANAC > Form 8-K on 30-Nov-2012All Recent SEC Filings

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Form 8-K for ANACOR PHARMACEUTICALS INC


30-Nov-2012

Other Events


ITEM 8.01 OTHER EVENTS.

On November 28, 2012, Anacor Pharmaceuticals, Inc. (Anacor) announced the completion of two Phase 1 safety studies of tavaborole for onychomycosis - a thorough QT (TQT), or cardiac safety, study and a Repeat Insult Patch Test (RIPT), which assessed skin sensitizing potential and cumulative irritation potential after repeated applications on skin. The announcement was made by Anacor's Chief Executive Officer, David P. Perry, at the Piper Jaffray Healthcare Conference in New York, New York. Tavaborole met the primary objectives in both of these safety studies.

The primary objective of the TQT trial was to assess the electrocardiogram (ECG) effects of tavaborole following multiple-dose administration of tavaborole 5% solution relative to vehicle in healthy adult male and female subjects. Preliminary results from this study demonstrate that tavaborole is safe and has no effect on heart rate, PR and QRS interval duration, cardiac morphology, or cardiac repolarization.

The primary objectives of the RIPT study were to determine the potential of tavaborole to induce sensitization or to cause irritation by repeated topical application to healthy skin. Preliminary results from the RIPT study indicate that tavaborole is not a skin sensitizing agent.


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