ITEM 8.01 OTHER EVENTS.

On November 15, 2012, AcelRx Pharmaceuticals, Inc. (the "Company") issued a press release announcing top-line results in a phase 3 non-inferiority study of sublingual Sufentanil NanoTab® PCA System vs. IV PCA morphine for post-operative pain. A copy of the press release is attached as Exhibit 99.1 to this report.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS.

(d) Exhibits.

Exhibit Number Description

99.1 Press Release dated November 15, 2012.

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