As previously reported on that certain Current Report on Form 8-K filed on May 9, 2012 by Marina Biotech, Inc. (the "Company") with the Securities and Exchange Commission (the "Original Form 8-K"), on May 3, 2012 the Company, together with its wholly-owned subsidiaries MDRNA Research, Inc. and Cequent Pharmaceuticals, Inc. (collectively, "Marina"), entered into a worldwide exclusive Intellectual Property License Agreement (the "License Agreement") with Monsanto Company ("Monsanto"), a global leader in agriculture and crop sciences, for Marina's delivery and chemistry technologies. Under terms of the License Agreement, the Company received $1.5 million in initiation fees, and may receive royalties on product sales in the low single digit percentages.

The Company is filing this Amendment on Form 8-K/A to amend the Original Form 8-K for the sole purpose of filing a redacted copy of the License Agreement as Exhibit 10.1 hereto. The Company has submitted a FOIA Confidential Treatment Request to the Securities and Exchange Commission pursuant to Rule 24b-2 under the Securities Exchange Act of 1934, as amended, requesting that it be permitted to redact certain portions of the License Agreement. The omitted material has been included in the request for confidential treatment.

The foregoing summary of the License Agreement is qualified in its entirety by reference to the License Agreement, a redacted copy of which is attached as Exhibit 10.1 to this Form 8-K/A.

(d) Exhibits

Exhibit No.   Description

10.1 (2)      Intellectual Property License Agreement, effective as of May 3,
              2012, by and between Marina Biotech, Inc., MDRNA Research, Inc.,
              Cequent Pharmaceuticals, Inc. and Monsanto Company.

99.1 (1)      Press release of Marina Biotech, Inc. dated May 8, 2012.

(1) Previously filed as an exhibit to the Original Form 8-K.

(2) Filed herewith. Portions of the exhibit have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended, and the omitted material has been separately filed with the Securities and Exchange Commission.