On November 13, 2012, KYTHERA Biopharmaceuticals, Inc. issued a press release relating to its financial results for the three and nine months ended September 30, 2012. The full text of the press release is furnished herewith as Exhibit 99.1.

The information in this Item 2.02 of this Form 8-K and the Exhibit 99.1 attached hereto shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that Section, or incorporated by reference in any filing under the Securities Act of 1933, as amended (the "Securities Act"), or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.

The following Exhibit is filed as part of this Current Report on Form 8-K.

(d) Exhibits

Exhibit Number      Description

     99.1           KYTHERA Biopharmaceuticals, Inc. Press Release Reporting Third
                    Quarter 2012 Financial Results dated November 13, 2012.