Item 2.02. Results of Operations and Financial Condition

On November 7, 2012, Nanosphere, Inc. (the "Company") issued a press release announcing its financial results for its third quarter ended September 30, 2012. A copy of the press release is furnished herewith as Exhibit 99.1.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

Exhibit Number Description

99.1 Press Release of Nanosphere, Inc. dated November 7, 2012.

The information included under Item 2.02, "Results of Operations and Financial Condition" and Item 9.01 "Financial Statements and Exhibits" of this Current Report on Form 8-K (including the exhibit attached hereto) is being furnished and such information (including the exhibit) shall not be deemed to be "filed" for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that Section, nor shall it be incorporated by reference into a filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such a filing. This Current Report (including the exhibit attached hereto) will not be deemed an admission as to the materiality of any information required to be disclosed solely to satisfy the requirements of Regulation FD.

---