On October 25, 2012, Pacific Biosciences of California, Inc. announced its financial results for the quarter ended September 30, 2012. A copy of the press release containing the announcement is included as Exhibit 99.1 and is incorporated herein by reference.

This information is intended to be furnished under Item 2.02 of Form 8-K, "Results of Operations and Financial Condition" and shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such a filing.

(d) Exhibits.

Exhibit
Number                                    Description

99.1         Press Release dated October 25, 2012 titled "Pacific Biosciences of
             California, Inc. Announces Third Quarter 2012 Financial Results"
             (furnished and not filed herewith solely pursuant to Item 2.02).