Item 5.02. Departure of Directors or Certain Officers; Election of Directors;
Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On September 11, 2012, Dr. Edward D. Wirth, III notified InVivo Therapeutics Holdings Corp. (the "Company") that he was resigning his position as Chief Science Officer of the Company, effective September 21, 2012. The Company's Board of Directors has appointed Brian Hess, Director of Product Development of the Company, to serve as Interim Chief Science Officer commencing September 21, 2012.

Mr. Hess, a former Stryker biomaterials product development specialist, joined InVivo as its Director of Product Development in February 2012. As Director of Product Development, Mr. Hess is responsible for managing, developing and maintaining the pipeline for the entire portfolio of InVivo products.

Prior to joining the Company, Mr. Hess spent the previous eight years at Stryker developing biomaterial technologies for the orthopedic market, and he has led multiple product development teams through the FDA process. Mr. Hess was instrumental in developing HydroSet™, an injectable calcium phosphate based bone substitute, from concept to product launch. The product has become the market-leading bone scaffold, and Stryker awarded Mr. Hess and his team with "Best Technology" and "Best Team Synergy" for their work on this critical product. Mr. Hess also won several research and development awards during his tenure at Stryker. Most notably he was named "Co-Innovator of the Year" in 2010 within Stryker Orthopeadics.

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