On August 23, 2012, CombiMatrix Corporation (the "Company") issued a press release announcing the hiring of Mark McDonough as Chief Commercial Officer of the Company. A copy of the press release is furnished herewith as Exhibit 99.1.

The information contained in this Item 7.01 and in the exhibit attached to this report is being furnished to the Securities and Exchange Commission and shall not be deemed "filed" for purposes of Section 18 of the Exchange Act, or otherwise subject to the liabilities of that Section, or incorporated by reference in any filing under the Exchange Act or the Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such a filing.

The Company has hired Mark McDonough to serve as its Chief Commercial Officer.

Mr. McDonough, 43, was Vice President, Sales, Customer Service and Training at Pathwork Diagnostics, Inc. from 2008 until August 2012. Prior to that, from 2002 to 2008, Mr. McDonough worked for USLabs/Dianon (when USLabs was acquired by LabCorp) and ultimately became Vice President of Sales. Mr. McDonough received a Bachelor's Degree in Finance from Miami University-Ohio.

(a) Financial Statements of Businesses Acquired.

Not applicable.

(b) Pro Forma Financial Information.

Not applicable.

(c) Shell Company Transactions.

Not applicable.

(d) Exhibits.

Exhibit No.                           Description of Exhibit

99.1          Press Release of CombiMatrix Corporation dated August 23, 2012
              (furnished herewith pursuant to Item 7.01).