Item 7.01 Regulation FD Disclosure

On August 1, 2012, Charles H. Majors, Chairman of the Board of Directors and Chief Executive Officer of American National Bankshares Inc. ("American National"), and Jeffrey V. Haley, President of American National and President and Chief Executive Officer of its subsidiary bank, American National Bank and Trust Company, will make a presentation at the Keefe, Bruyette & Woods 13th Community Bank Conference to be held in New York, New York. The presentation is scheduled for approximately 10 a.m. Eastern Daylight Time. A copy of the presentation will be made available at American National's website (http://www.amnb.com) and is attached as Exhibit 99.1 to this report and incorporated herein by reference.

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Item 9.01 Financial Statements and Exhibits

(d) Exhibits:

99.1 Updated Investor Presentation

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Date: August 1, 2012 /s/ William W. Traynham
Senior Vice President and Chief Financial Officer