Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

As contemplated by the prospectus related to the initial public offering of Durata Therapeutics, Inc. (the "Company"), the Company's Board of Directors (the "Board") appointed a new independent director to the Board to replace one of the Company's existing directors who is transitioning off the Board.

On July 20, 2012, Mr. George Horner III, a member of the Board, provided notice of his resignation from the Board effective August 3, 2012. Mr. Horner is transitioning off the Board in order to pursue other opportunities and not because of any disagreement with the Company on any matter relating to the Company's operations, policies or practices.

On July 25, 2012, the Board elected, effective August 3, 2012, Lisa Giles, to fill the vacancy on the Board created by the resignation of Mr. Horner.

A copy of the press release announcing Ms. Giles's appointment and Mr. Horner's resignation is attached as Exhibit 99.1 to this Current Report on Form 8-K.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits:

99.1 Press release dated July 26, 2012.

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