Summary of ASTEX PHARMACEUTICALS, INC

Item 5.07. Submission of Matters to a Vote of Security Holders.

The Annual Meeting of Stockholders of Astex Pharmaceuticals, Inc., a Delaware corporation (the "Company") was held on June 22, 2012. The proposals submitted to a vote of the stockholders at the meeting are described in detail in the Company's definitive proxy statement filed with the Securities and Exchange Commission on April 30, 2012. The final results of voting for each matter are as follows:

Proposal 1: Election of the Board of Directors of the Company.

                                                       Broker
Nominee                Votes For    Votes Withheld   Non-Votes

Charles J. Casamento   48,842,552        2,570,723   27,978,343
Peter Fellner          46,581,175        4,832,100   27,978,343
Thomas V. Girardi      47,253,044        4,160,231   27,978,343
Allan R. Goldberg      49,172,563        2,240,712   27,978,343
Timothy Haines         49,220,461        2,192,814   27,978,343
Harren Jhoti           48,196,215        3,217,060   27,978,343
Ismail Kola            47,429,512        3,983,763   27,978,343
Walter J. Lack         45,121,623        6,291,652   27,978,343
James S.J. Manuso      47,776,777        3,636,498   27,978,343

Proposal 2 Approval of amendments to the Company's 2003 Stock Plan.

Votes For:          41,402,030
Votes Against:       9,826,201
Votes Abstaining:      185,044
Broker Non-Votes:   27,978,343

Proposal 3: Ratification of Ernst & Young LLP as independent registered public accounting firm for the year ending December 31, 2012.

Votes For:          76,052,929
Votes Against:       2,882,430
Votes Abstaining:      456,259

Proposal 4: Non-binding advisory vote to approve executive compensation.

Votes For:          45,125,083
Votes Against:       5,017,267
Votes Abstaining:    1,270,925
Broker Non-Votes:   27,978,343

Each of Proposals 1 through 4 set forth above was approved.