Item 5.02. Departure of Directors or Principal Officers; Election of Directors;
Appointment of Principal Officers; Compensatory Arrangements of Certain Officers.

On June 7, 2012, Chelsea Therapeutics International, Ltd. issued a press release announcing voluntary reductions in compensation for senior management team members, all of whom are named executive officers, and directors as part of cost containment initiatives to reduce expenses. A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

Item 8.01. Other Events.

On June 7, 2012, Chelsea Therapeutics International, Ltd. issued a press release announcing voluntary reductions in compensation for senior management team members and directors and other cost containment initiatives to reduce expenses. A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits

Exhibit No. Description

99.1 Press release dated June 7, 2012.