The 2012 Annual Meeting of Shareholders of Omeros Corporation was held on June 1, 2012. Shareholders of record at the close of business on April 2, 2012 were entitled to vote up to 22,451,837 shares of common stock at the annual meeting. A total of 18,046,309 (80.38%) shares were represented at the annual meeting in person or by proxy. The following is a brief description of each matter voted upon at the annual meeting and the number of votes cast for, against or withheld, as well as the number of abstentions and broker non-votes, as to each such matter:

(1) The election of the following two Class III directors, each to serve until the 2015 Annual Meeting of Shareholders or until his successor is duly elected and qualified or until his earlier death, resignation or removal:

                                         For      Withheld   Broker Non-Votes
         Gregory A. Demopulos, M.D.   8,883,450   305,831       8,857,028

         Leroy E. Hood, M.D., Ph.D.   9,040,954   148,327       8,857,028

(2) The ratification of the appointment of Ernst & Young LLP as Omeros' independent registered public accounting firm for the fiscal year ending December 31, 2012.

For Against Abstain Broker Non-Votes 17,798,621 138,400 109,288 0