The annual meeting of the stockholders (the "Meeting") of Affymetrix, Inc. ("Affymetrix") was held on May 11, 2012. 58,762,989 shares of Affymetrix common stock were present at the Meeting, representing 83.4% of a total of 70,452,511 shares of common stock outstanding and eligible to vote at such time.

1. With respect to the election of the eight nominees as Directors of Affymetrix:

                                For            Against       Abstain
Stephen P.A. Fodor, Ph.D.     47,257,800         957,673       32,141
Frank Witney                  47,712,230         493,093       42,291
Nelson C. Chan                46,150,217       2,054,221       43,176
John D. Diekman, Ph.D.        47,482,187         720,992       44,435
Gary S. Guthart, Ph.D.        41,119,831       7,084,354       43,429
Jami Dover Nachtsheim         41,113,152       7,092,380       42,082
Robert H. Trice, Ph.D.        47,443,551         760,374       43,689
Robert P. Wayman              47,446,327         759,171       42,116

Consequently, all nominees were elected to the Board of Directors by the stockholders of Affymetrix.

1. With respect to the ratification of the appointment of Ernst & Young LLP as the independent registered public accounting firm of Affymetrix for the fiscal year ending December 31, 2011:

For Against Abstain 58,327,858 362,508 72,623

2. With respect to the approval of the 2011 Employee Stock Purchase Plan:

For Against Abstain 47,021,450 745,357 480,807

3. With respect to the advisory vote to approve executive compensation:

For Against Abstain 25,742,831 22,353,926 150,857

Board of Directors Leadership

On May 11, 2012, the independent Directors of Affymetrix elected Robert P. Wayman as the Company's lead director.