On May 10, 2012, Alexza Pharmaceuticals, Inc., a Delaware corporation, issued a press release reporting financial results for the fiscal quarter ended March 31, 2012 and provided a business update. The press release is attached hereto as Exhibit 99.1, which is furnished under Item 2.02 of this report and shall not be deemed to be "filed" for purposes of Section 18 of the Securities Exchange Act of 1934 (the "Exchange Act") or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, regardless of any general incorporation language in such filing.

(d) Exhibits.

Exhibit Number        Description

99.1                  Press Release titled "Alexza Reports 2012 First Quarter
                      Financial Results and Provides Business Update," dated May 10,
                      2012.