Item 8.01. Other Events.

On April 23, 2012, Ironwood Pharmaceuticals, Inc. (the "Company") issued a press release announcing that the U.S. Food and Drug Administration notified the Company that it will require a three-month extension to complete its review of the data supporting the New Drug Application for linaclotide for the treatment of irritable bowel syndrome with constipation and chronic constipation. A copy of the press release is furnished as Exhibit 99.1 and is incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No. Description

99.1 Ironwood Pharmaceuticals, Inc. Press Release dated April 23, 2012

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