ITEM 7.01 REGULATION FD DISCLOSURE.

Comerica Incorporated ("Comerica") previously announced that Ralph W. Babb, Jr., Chairman and Chief Executive Officer of Comerica, will make a presentation at the Sandler O'Neill & Partners, L.P. 2009 East Coast Financial Services Conference on Thursday, November 12, 2009. Elizabeth S. Acton, Executive Vice President and Chief Financial Officer, and John M. Killian, Executive Vice President - Credit Policy, also will participate. Comerica's presentation will begin at 7:10 a.m. ET. To access the live audio webcast, visit the "Investor Relations" area of Comerica's website at www.comerica.com. Replays will be available at the same location following the conference. A copy of the presentation slides, which will be discussed at that conference, is attached hereto as Exhibit 99.1.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS.

(d) Exhibits

99.1 Sandler O'Neill East Coast Financial Services Conference Presentation Slides

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