Item 1.01. Entry into a Material Definitive Agreement.
On November 3, 2009, we entered into a third amendment to the Exclusive License
of Technology Agreement dated October 14, 2005 and as amended thereafter,
between us and Isis Innovation Limited, under which we in-licensed fundamental
patented noninvasive prenatal diagnostic technology, including US Patent
No. 6,258,540. Pursuant to the amendment, Isis Innovation has agreed to a
modification of certain time-based commercial launch milestones relating to
aneuploidy and other products. In exchange for this modification, we have agreed
to make an immediate one-time payment of $1,000,000, increase royalty payments
under the agreement during the final 12 months of the patent term and increase
the specified minimum royalty amounts.
2.
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