On November 4, 2009, Affymax, Inc. issued a press release announcing its financial results for the quarterly period ended September 30, 2009. The press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

The information in this Report on Form 8-K, including the exhibit hereto, shall not be deemed to be "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended. The information contained herein and in the accompanying exhibit shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission made by Affymax, Inc. whether made before or after the date hereof, regardless of any general incorporation language in such filing.

(d) Exhibits:

Exhibit No.                                Description

99.1          Press Release entitled "Affymax® Reports Third Quarter 2009 Financial
              Results," dated November 4, 2009.