Item 7.01. Regulation FD Disclosure.

On October 15, 2009, AspenBio Pharma, Inc. (the "Company") issued a letter to its shareholders titled - "AspenBio Pharma Progress Update." The letter is furnished as Exhibit 99.1 to this Form 8-K.

The shareholders' letter references a Company webcast that includes the power point presentation furnished as Exhibit 99.2 to this Form 8-K. The power point presentation is also available on the Company's website.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits

Exhibits

99.1 Shareholder letter, dated October 15, 2009, issued by AspenBio Pharma, Inc. titled "AspenBio Pharma Progress Update."
99.2 Company information - "Power Point Presentation" dated October 2009.