On September 23, 2009, MediciNova, Inc. ("MediciNova") and Danerius, LLC, an affiliate of Alan W. Dunton, M.D., one of the directors of MediciNova, entered into a First Amendment (the "Amendment") to the Consulting Agreement between the parties dated as of June 12, 2009 (the "Consulting Agreement"), pursuant to which the term of the Consulting Agreement was extended for a period of two years. The Consulting Agreement will now expire on October 12, 2011, subject to either party providing written notice of termination or MediciNova terminating the agreement for breach. A copy of the Amendment is attached hereto as Exhibit 10.1 and is incorporated herein by reference.

A discussion of the material terms of the Consulting Agreement is included in MediciNova's Current Report on Form 8-K filed with the Securities and Exchange Commission on June 16, 2009, which includes as Exhibit 10.1 thereto a copy of the Consulting Agreement.

(d) Exhibits.

Exhibit No.       Description

10.1              First Amendment to Consulting Agreement by and between
                  MediciNova, Inc. and Danerius, LLC, dated as of September 23,
                  2009