Item 1.01 Entry into a Material Definitive Agreement.

On September 17, 2009, Antares Pharma, Inc. (the "Company") entered into definitive subscription agreements (the "Subscription Agreements") with certain institutional investors relating to the issuance and sale (the "Offering") of 2,727,273 units (the "Units"), each Unit consisting of (i) one share of common stock of the Company (the "Common Stock") and (ii) one warrant to purchase 0.4 of a share of Common Stock (for a total of 1,090,909 shares of Common Stock) at a purchase price of $1.10 per Unit. A copy of the form of subscription agreement is filed as Exhibit 10.1 to this Current Report and is incorporated herein by reference.

The warrants will be exercisable beginning any time on or after the date six months following the date of closing of the Offering, expire on the fifth anniversary of the closing of the Offering and have an exercise price equal to $1.15 per share. The form of warrant to be issued to the purchasers of Units in connection with the Offering is included as Exhibit 4.1 to this Form 8-K and is incorporated herein by reference.

The closing of the Offering is expected to take place on or about September 23, 2009, subject to the satisfaction of customary closing conditions. Net proceeds from the Offering are estimated to be approximately $2,925,000, after deducting estimated offering expenses payable by the Company.

The Units were registered under an existing shelf registration statement on Form S-3 (Registration No. 333-158630) which was declared effective by the Securities and Exchange Commission on May 6, 2009. The prospectus supplement describing the terms of the Offering will be filed with the Securities and Exchange Commission and a free writing prospectus was filed with the Securities and Exchange Commission on September 17, 2009. A copy of the opinion of Morgan, Lewis & Bockius LLP relating to the legality of the issuance and sale of the Units in the Offering is attached as Exhibit 5.1 to this Form 8-K.

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Item 9.01. Financial Statements and Exhibits.

(d) Exhibits. Exhibit 4.1 Form of Warrant. Exhibit 5.1 Opinion of Morgan, Lewis & Bockius LLP. Exhibit 10.1 Form of Subscription Agreement.

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