Item 1.01 Entry into a Material Definitive Agreement

On August 14, 2009, Bioject Medical Technologies Inc. entered into Convertible Subordinated Promissory Note Third Extension Agreements (the "Third Extensions") with each of Life Sciences Opportunities Fund II (Institutional), L.P. and Life Sciences Opportunities Fund II, L.P. (collectively, the "LOF Funds") relating to those two Convertible Subordinated Promissory Notes, dated as of December 5, 2007, issued by Bioject to the LOF Funds in the aggregate principal amount of $600,000 (the "Notes"). The Third Extensions extend the maturity date of the Notes from August 15, 2009 to August 31, 2009.

Item 9.01 Financial Statements and Exhibits

(d) Exhibits

The following exhibits are filed herewith and this list is intended to constitute the exhibit index:

10.1 Convertible Subordinated Promissory Note Third Extension Agreement, dated August 14, 2009, between Bioject Medical Technologies Inc. and Life Sciences Opportunities Fund II, L.P.

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