Item 8.01 Other Events.

On May 14, 2009, at the 2009 Annual Meeting of Stockholders of ArQule, Inc. (the "Registrant") the stockholders voted:

1. To elect Timothy C. Barabe and Paolo Pucci as directors of the Registrant to hold office for a term of three years and until their respective successors are elected and qualified;

2. To approve amendments to the Registrant's Amended and Restated 1994 Equity Incentive Plan to increase the number of shares of common stock available for awards granted under the Plan by 1,400,000, from 9,600,000 to 11,000,000 shares of common stock and to incorporate other changes described in the Registrant's proxy statement;

3. To approve amendments to the Registrant's Amended and Restated 1996 Employee Stock Purchase Plan to increase the number of shares of common stock available for purchase by participants under the Plan by 400,000, from 1,600,000 to 2,000,000 shares of common stock; and

3. To ratify the appointment of PricewaterhouseCoopers LLP, an independent registered public accounting firm, to audit the Registrant's financial statements for the fiscal year ending December 31, 2009.

The voting results are set forth in Exhibit 99.1 to this report and incorporated herein by reference.