On June 15, 2009, Enzo Biochem, Inc. (the "Company") issued a press release announcing its operating results for the three months ended April 30, 2009 and that it will conduct a conference call to discuss the results on Tuesday, June 16, 2009, at 8:30 a.m., Eastern time. The details of how to participate in the call are set forth in the press release.

The Company also announced that it will not file its quarterly report on Form 10-Q for its fiscal quarter ended April 30, 2009 with the Securities and Exchange Commission prior to the expiration of the extension period provided under Rule 12b-25 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended (the "Exchange Act"). The Company had filed a Notification of Late Filing on Form 12b-25 with the Securities and Exchange Commission on June 10, 2009 disclosing that it was not able to timely file its quarterly report on Form 10-Q for its fiscal quarter ended April 30, 2009 on or prior to the required deadline of June 9, 2009, but that it anticipated doing so within the extension period of five calendar days provided under Rule 12b-25 under the Exchange Act.

A copy of the press release is furnished as Exhibit 99.1 attached hereto and is incorporated by reference in its entirety into this Item 2.02 of this Current Report on Form 8-K.

In accordance with General Instruction B.2. of Form 8-K, the information contained in this Current Report on Form 8-K, including Exhibit 99.1, is being furnished and shall not be deemed to be "filed" for purposes of Section 18 of the Exchange Act or otherwise subject to the liability of that section. Such information shall not be incorporated by reference in any filing of the Company, whether made before or after the date hereof, regardless of any general incorporation language in such filing, except as otherwise expressly set forth by specific reference in such a filing.

The information provided in Item 2.02 of this Current Report on Form 8-K is incorporated herein by reference in its entirety.

Item 9.01.     Financial Statements and Exhibits.

(d)       Exhibits. The following exhibit is furnished herewith:

Exhibit No.   Description

99.1          Press Release of Enzo Biochem, Inc. discussing financial results for third
              fiscal quarter ended April 30, 2009.