On May 29, 2009, Neurobiological Technologies, Inc. (the "Company") and ICON Clinical Research Limited ("ICON") mutually agreed to terminate the Master Clinical Services Agreement dated January 16, 2007 (the "Agreement") and all work orders and change orders related to the Agreement. The Company and ICON entered into a Termination Agreement to Master Clinical Services Agreement and Work Order No. 1 and 2, effective as of May 29, 2009 (the "Termination Agreement"). The Company agreed to make a final payment to ICON in settlement of all unpaid costs incurred by ICON and the termination of ICON's services.

A complete copy of the Termination Agreement is filed herewith as Exhibit 10.1 and incorporated herein by reference. The foregoing description of the terms of the Termination Agreement is qualified in its entirety by reference to such exhibit.

(d) Exhibits

Exhibit No.       Description
10.1              Termination Agreement to Master Clinical Services Agreement and
                  Work Order No. 1 and 2, dated May 29, 2009, between
                  Neurobiological Technologies, Inc. and ICON Clinical Research
                  Limited