Item 7.01 Regulation FD Disclosure.

Glenn E. Moyer, President and CEO of National Penn Bancshares, Inc. ("NPB"), Michael R. Reinhard, CFO of NPB, and Michelle H. Debkowski, IRO of NPB, presented at the SunTrust Robinson Humphrey Financial Services Unconference on May 19, 2009. The slides that accompanied the presentation are furnished in this report, pursuant to this Item 7.01, as Exhibits 99.1, and are incorporated herein by reference. Without limiting the generality of the foregoing, the text of the slide entitled "Safe Harbor Regarding Forward Looking Statements" is incorporated by reference into this Item 7.01. No part of this report shall be deemed incorporated by reference into any registration statement filed under the Securities Act of 1933.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits

99.1 Slide presentation for National Penn Bancshares, Inc. made on May 19, 2009 (furnished pursuant to Item 7.01 hereof).

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