Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

(b) SuperGen, Inc. issued a press release announcing that Gregory Berk, M.D., Chief Medical Officer, has left the Company effective on May 1, 2009.

Michael D. Young, M.D., Ph.D., a current member of SuperGen's board of directors, will serve as SuperGen's interim Chief Medical Advisor, consulting to James S.J. Manuso, Ph.D. Dr. Manuso will oversee clinical and regulatory development until a replacement for Dr. Berk can be found. Dr. Young will continue to serve on SuperGen's board of directors.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits

Exhibit No. Description
99.1 Press Release dated May 1, 2009, of SuperGen, Inc.

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