The Company is filing this Current Report on Form 8-K solely to correct an inadvertent omission from the Grants of Plan-Based Awards table included in its 2008 Proxy Statement distributed in connection with its Annual Meeting of Stockholders held in August 2008. The table included in the Proxy Statement inadvertently included duplicate numbers in the last two columns. The Company has set forth below the corrected table indicating the revised information in the last column:

                                                           All Other
                                          All Other      Option Awards:
                                         Stock Awards:      Number of     Exercise or     Grant Date
                                          Number of        Securities     Base Price of  Fair Value of
                                        Shares of Stock    Underlying        Option        Stock and
                                           or Units          Options         Awards      Option Awards
           Name            Grant Date         (#)              (#)            ($)             ($)

Howard Solomon              12/06/07      60,000 (1)      125,000 (2)       37.2550       4,651,263
Lawrence S. Olanoff,        12/06/07      40,000 (1)       75,000 (2)       37.2550       2,939,778
M.D., Ph.D.
Elaine Hochberg             12/06/07      25,000 (3)       50,000 (4)       37.2550       1,691,110
Francis I. Perier, Jr.      12/06/07      20,000 (3)       50,000 (4)       37.2550       1,504,835
Ivan Gergel, M.D.           12/06/07      15,000 (3)       30,000 (4)       37.2550       1,014,666

(1) The stock award is subject to a risk at forfeiture which lapses as to 25% of the shares covered by the award on the six month anniversary of the grant date and as to 25% of the shares covered by the award on each of the first three anniversaries of the grant date.
(2) The stock option has a term of ten years and becomes exercisable as to all of the shares covered by the option on the six month anniversary of the grant date.
(3) The stock award is subject to a risk at forfeiture which lapses as to 25% of the shares covered by the award on each of the first, second, third and fourth anniversaries of the grant date.
(4) The stock option has a term of ten years and vests and is exercisable as to 15% of the shares covered by the option on the first, second, third and fourth anniversaries of the grant date and as to the remaining 40% of the shares covered by the option on the fifth anniversary of the grant date.