Item 1.01. Entry into a Material Definitive Agreement

On March 27, 2009, Northwest Biotherapeutics, Inc. (the "Company") received funds of $110,000 from a private investor ("INVESTOR"). The investment is in the form of a promissory note ("NOTE") that is an unsecured obligation of the Company and accrues interest at the rate of 6% per year. The maturity date of the Note will be two years for date of issuance. The Note may be prepaid at the discretion of the Company at any time prior to maturity, without any prepayment penalty and at the discretion of the Company. The Note also contains customary representations, warranties and covenants.

Item 2.03. Creation of a Direct Financial Obligation or an
Obligation under an Off-Balance Sheet Arrangement of a Registrant.

The disclosure under Item 1.01 of this Form 8-K is incorporated into this Item 2.03 by this reference.

Item9.01. Financial Statements and Exhibits.

(a) Financial Statements of Businesses Acquired: Not Applicable

(b) Pro Forma Financial Information: Not Applicable

(c) Shell Company Transactions: Not Applicable

(d) Exhibits.

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