Item 5.02. Departures of Directors or Certain Officers; Election of
Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

(b) and (c) Effective March 2, 2009, Kevin Krenitsky MD has replaced Shahram K. Rabbani as President of Enzo Clinical Labs, Inc. ("Enzo Labs"), a wholly-owned subsidiary of Enzo Biochem, Inc. (the "Company"). Prior to joining the Enzo Labs, Dr. Krenitsky served as the Chief Executive Officer (CEO) of BioServe, a Maryland based genomics services company that provides genetic analysis to pharmaceutical and research organizations. In this capacity, Dr. Krenitsky led a team of highly competent executives in a global expansion of the company, by extending institutional equities and executing strategic acquisitions. From 2006 to 2007, Dr. Krenitsky served as the CEO of Parkway Clinical Labs ("Parkway"), which is a regional full service and esoteric reference laboratory in Pennsylvania. From 2005 to 2006, Dr. Krenitsky served as Parkway's Senior Vice President and Division Head, and from 2004 to 2005 he served as Parkway's Senior Vice President of Business Development. The Company believes that Dr. Krenitsky's experience and talent will be a key component to achieving our business goals.

There are no family relationships between Dr. Krenitsky and any of the executive officers or directors of the Company or any of its affiliates.

---