Item 2.02 Results of Operations and Financial Condition and Item 7.01 Regulation FD Disclosure.

On February 25, 2009, Express Scripts, Inc. (the "Company") issued a press release with respect to its results of operations for the period-ending December 31, 2008. The press release is attached hereto as Exhibit 99.1 and incorporated herein by reference.

The information contained in this Current Report on Form 8-K, including the accompanying Exhibit 99.1, is being furnished pursuant to Item 2.02 and Item 7.01 of Form 8-K and shall not be deemed to be "filed" for purposes of
Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liability of that section. The information contained in this Current Report on Form 8-K, including the accompanying Exhibit 99.1, shall not be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, whether made before or after the date hereof, except as shall be expressly set forth by specific reference in such a filing.

Item 9.01 Financial Statements and Exhibits

(c) The following Exhibits are furnished as part of this report on Form 8-K:

Exhibit 99.1 Press Release, dated February 25, 2009

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