Item 7.01 Regulation FD Disclosure

At an investors' conference today, management of Express Scripts, Inc. (the "Company") reaffirmed that the Company expects its 2009 diluted earnings per share to be in a range of $3.63 to $3.73.

SAFE HARBOR STATEMENT

This report contains forward-looking statements, including, but not limited to, statements related to the Company's plans, objectives, expectations (financial and otherwise) or intentions. Actual results may differ significantly from those projected or suggested in any forward-looking statements. Factors that may impact these forward-looking statements can be found in the Management's Discussion and Analysis of Financial Condition and Results of Operations in our Form 10-Q on file with the SEC. A copy of this form can be found at the investor relations section of Express Scripts web site at http://www.express-scripts.com

We do not undertake any obligation to release publicly any revisions to such forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.