Item 5.02. Departure of Directors or Certain Officers; Election of
Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

NovaBay Pharmaceuticals, Inc. announced that Dr. Colin Scott, its VP, Clinical Research and Development, has resigned from the company effective December 31, 2008 to take up a position in his area of expertise in pulmonary medicine that will allow him to be closer to his family. Dr. Scott is transferring his responsibilities to Dr. Kenneth Krantz, M.D., Ph.D., who has been NovaBay's VP of Medical Affairs since 2004 and to Susan Iovino, who has been our Director of Clinical Operations for the past two years.

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