At the 2008 special meeting (the "Special Meeting") of stockholders of PolyMedix, Inc. (the "Company") on December 10, 2008, the Company's stockholders approved an amendment (the "Amendment") to the Company's Certificate of Incorporation to increase the number of shares of common stock, par value $0.001 per share ("Common Stock") authorized for issuance by the Company from 90,000,000 to 250,000,000 shares. The Amendment became effective on December 10, 2008 upon filing with the Secretary of State of the State of Delaware. As a result of the effectiveness of the increase, each share of the Company's Series 2008 Convertible Preferred Stock then outstanding automatically converted into 10 shares of Common Stock and each of the Company's Series B Warrants then outstanding became exercisable for 10 shares of Common Stock at an exercise price of $1.00 per share.

The information disclosed in Item 8.01 and the full text of the Amendment, which is attached as Exhibit 3.1 to this Report, are incorporated herein by reference.

At the Special Meeting, the following five proposal was considered:

To increase the number of shares of Common Stock authorized for issuance by the Company from 90,000,000 to 250,000,000 shares:

      Number of Shares   Number of Shares Voted
         Voted For              Against           Abstentions   Broker Non-Votes
         34,851,755             916,084             211,236            0