Item 5.03 Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year.

On December 9, 2008, the Board of Directors (the "Board") of Amgen Inc. (the "Company") approved an amendment (the "Amendment") to the Company's Amended and Restated Bylaws, which became effective upon its adoption by the Board on December 9, 2009. Among other things, the Amendment removes the sole remaining supermajority voting requirement and modifies certain advance notice provisions, which are described in greater detail below.

Elimination of Supermajority Voting

The Amendment replaces a provision requiring a vote of 66-2/3% of the outstanding shares of stock entitled to vote in order to amend, repeal or adopt new bylaws, with a majority voting requirement consistent with the other stockholder approval thresholds in the Company's Amended and Restated Bylaws.

Modifications to Advance Notice Provisions

The Amendment modifies the advance notice provisions in the Company's Amended and Restated Bylaws by requiring that additional information be furnished in connection with nominations and other business proposals, clarifying that the advance notice provisions apply to all stockholder nominations and other business proposals and effecting other technical changes to the requirements applicable to stockholder nominations and other business proposals.

Section 15(a)(2) of the Amendment requires, among other things, that the following disclosure be provided with respect to nominations and business proposals that stockholders seek to present at any meeting of stockholders:

• information regarding nominees for election to the Board, including information regarding the nominee's eligibility to serve as a director, whether the proponent received payment for making the nomination and required disclosure under federal securities laws;

• information regarding business proposals, including a description of why the proposal was made and whether the proponent received payment relating to the proposal; and

• information regarding the proponent, including disclosure regarding the class or series and number of shares beneficially owned by the proponent, a description of any agreement among any group of persons making the proposal and disclosure regarding hedging and derivative transactions entered into by such group.

In addition, Section 15(c)(3) of the Amendment clarifies that the advance notice provisions apply to all stockholder nominations and other business proposals, whether or not they are to be included in the Company's annual proxy statement, and provides that such provisions are the exclusive means of making nominations or other business proposals. However, the Amendment continues to treat business proposals that are submitted in compliance with Rule 14a-8 (or any successor thereof) promulgated under the Securities Exchange Act of 1934, as amended, and included in the Company's proxy statement as having been made in compliance with the advance notice bylaw.

The preceding disclosure is qualified in its entirety by reference to the Amendment, a copy of which is attached hereto as Exhibit 3.1 and is incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits.

3.1 Second Amendment to the Amended and Restated Bylaws

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