Exhibit 100 to this Current Report on Form 8-K contains documents formatted in XBRL (eXtensible Business Reporting Language) with information from Comerica Incorporated's Quarterly Report on Form 10-Q for the quarter ended September 30, 2008, filed with the Securities and Exchange Commission (SEC) on October 31, 2008. The information includes the (i) Consolidated Balance Sheets at September 30, 2008, December 31, 2007 and September 30, 2007; (ii) Consolidated Statements of Income for the three months and nine months ended September 30, 2008 and 2007; (iii) Consolidated Statements of Changes in Shareholders' Equity for the nine months ended September 30, 2008 and 2007; (iv) Consolidated Statements of Cash Flows for the nine months ended September 30, 2008 and 2007; and (v) the Notes to Consolidated Financial Statements, tagged as blocks of text.

Users of this data are advised pursuant to Rule 401 of Regulation S-T that the financial and other information contained in the XBRL documents is unaudited, and these are not the financial statements of Comerica Incorporated as filed with the SEC. The purpose of submitting these XBRL documents is to test the related format and technology and, as a result, investors should not rely on the information in this Current Report on Form 8-K, including Exhibit 100, in making investment decisions.

In accordance with Rule 402 of Regulation S-T, the information in this Current Report on Form 8-K, including Exhibit 100, shall not be deemed to be "filed" for purposes of Section 11 of the Securities Act of 1933, as amended (Securities Act), or Section 18 of the Securities Exchange Act of 1934, as amended (Exchange Act), or otherwise subject to the liabilities of these sections, and are not part of any registration statement to which they relate, and shall not be incorporated by reference into any registration statement or other document filed under the Securities Act or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.

(d) Exhibits

The following materials from Comerica Incorporated's Quarterly Report on Form 10-Q for the quarter ended September 30, 2008, filed on October 31, 2008 formatted in XBRL: (i) Consolidated Balance Sheets at September 30, 2008, December 31, 2007 and September 30, 2007; (ii) Consolidated Statements of Income for the three months and nine months ended September 30, 2008 and 2007;
(iii) Consolidated Statements of Changes in Shareholders' Equity for the nine months ended September 30, 2008 and 2007; (iv) Consolidated Statements of Cash Flows for the nine months ended September 30, 2008 and 2007; and (v) the Notes to Consolidated Financial Statements, tagged as blocks of text, are furnished as exhibits to this Current Report on Form 8-K and are collectively referred to as Exhibit 100:

100.INS   XBRL Instance Document
100.SCH   XBRL Taxonomy Extension Schema Document
100.CAL   XBRL Taxonomy Extension Calculation Linkbase Document
100.DEF   XBRL Taxonomy Extension Definition Linkbase Document
100.LAB   XBRL Taxonomy Extension Label Linkbase Document
100.PRE   XBRL Taxonomy Extension Presentation Linkbase Document