ITEM 1.02 Termination of a Material Definitive Agreement
On November 21, 2008 the Company terminated its Distribution Agreement for anesthetics for the human market in the United States with RxElite Holdings, Inc. (RxElite), a wholly owned subsidiary of RxElite Inc. (OTC BB:RXE.OB).
On November 25, 2008 the Company issued a press release announcing the termination, which is attached as Exhibit 99.1 and incorporated herein by reference.
ITEM 8.01 Other Events
On November 20, 2008, the Company issued a press release announcing a reduction of its workforce by approximately 50 positions. A copy of the press release announcing the workforce reduction is attached hereto as Exhibit 99.2.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS
(d) Exhibits
99.1 Press Release of Minrad International, Inc, dated November 25, 2008

99.2 Press Release of Minrad International, Inc, dated November 20, 2008.

---